Which of these steps in krebs' cycle indicates substrate level phosphorylation?

Conversion of succunic acid to a-ketoglutaric acid

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Conversion of succunic acid to malic acid

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Conversion of succunyl CoA to succunic acid

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Conversion of malic acid to oxaloacetic acid

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Solution

The correct option is C Conversion of succunyl CoA to succunic acid
Succinate thiokinase catalyzes the conversion of succinyl CoA to succinic acid. During this step, CoA is released and one molecule of GTP is formed from GDP. This is a substrate level phosphorylation.
Thus, the correct answer is 'Conversion of succinyl CoA to succinic acid.'

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