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Question

Which one is not a cofactor?

A
Co-enzyme
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B
Apoenzyme
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C
Prosthetic group
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D
Metal ions
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Solution

The correct option is B Apoenzyme
An apoenzyme is an inactive enzyme, activation of the enzyme occurs upon binding of an organic or inorganic cofactor. A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity. Cofactors can be considered "helper molecules" that assist in biochemical transformations. Cofactors can be divided into two major groups: organic Cofactors, such as flavin or heme, and inorganic cofactors, such as the metal ions Mg2+, Cu+, Mn2+, or iron-sulfur clusters.

A coenzyme is an organic non-protein compound that binds with an enzyme to catalyze a reaction. Coenzymes are often broadly called cofactors, but they are chemically different. A coenzyme cannot function alone, but can be reused several times when paired with an enzyme.

So the correct option is 'Apoenzyme'.






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