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Question

Which one is not applicable to RNA

A
Complementary base pairing
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B
5' phosphoryl and 3' hydroxyl ends
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C
Heterocyclic nitrogenous bases
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D
Chargaff s rule
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Solution

The correct option is D Chargaff s rule
RNA is usually single-stranded polynucleotide.
Erwin Chargaff proposed that the ratio between adenine and thymine and guanine and cytosine are equal and constant.
Due to the single-stranded nature, there is no specific relation between purine and pyrimidine contents, thus the guanine content is not equal to cytosine ( as in the case of DNA).
So, the correct option is 'Chargaff s rule'

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