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Question

Which one is the last electron acceptor over ETC in oxidative phosphorylation ?

A
Cyt b
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B
CO2
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C
H2
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D
Cyt a3
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Solution

The correct option is D Cyt a3
Electron transport chain

Electrons produced in the mitochondrial matrix from NADH are transferred through FMN and Fe-S centers to ubiquinone present in the inner membrane.

Then the electrons are transferred from reduced ubiquinone to cytochrome c via cytochrome b and c1 complex (complex III).
Cyt c acts as a carrier between complex III and IV.

The electrons from cyt c reaches complex IV which contains two copper centres cyt a and cyt a3.

Although oxygen is the final electron acceptor in ETC but among the options given cyt a3 can be regarded as the last electron acceptor.



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