Question

Which one of following is complex V of the ETS of inner mitochondrial membrane?

• A. NADH dehydrogenase
• B. Cytochrome oxidase
• C. Ubiquinone
• D. Succinate dehydrogenase
• E. ATP synthase

Answer 1

The correct option is E ATP synthase

Cofactors NADH and FADH2, generated during Glycolysis and Krebs cycle, donate their electrons to the electron transport system (complex I - complex IV) located on the inner membrane of the mitochondria and help create a proton gradient.
The complex V of ETS is the ATP synthase and it utilises the proton gradient created by the previous complexes of ETS to generate ATP.
ATP synthase contains a head piece, a stalk and a base piece. Out of these, the head piece is identified as the coupling factor 1 $F_1$, stalk portion is necessary for binding $F_1$ to inner mitochondrial membrane and the base piece is identified as $F_0$ and present within the inner mitochondrial membrane.