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Question

Which one of the following does not filter out from blood to Bowman's capsule in glomerular ultrafiltration?

A
Amino acids
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B
Polypeptide
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C
Glucose
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D
Fatty acids
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Solution

The correct option is B Polypeptide
The process of filtration of the blood in the Bowman's capsule is ultrafiltration or glomerular filtration. Any proteins that are roughly 30 kilodaltons or under can pass freely through the membrane. Any small molecules such as water, glucose, salt (NaCl), amino acids, and urea pass freely into Bowman's space, but cells, platelets and large proteins do not. As a result, the filtrate leaving the Bowman's capsule is very similar to blood plasma in composition as it passes into the proximal convoluted tubule.
So, the correct answer is option B.

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