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Question

Which one of the following genetic disease is sex – linked?


A

Royal Haemophilia

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B

Tay- Sachs disease

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C

Cystic fibrosis

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D

Hypertension

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Solution

The correct option is A

Royal Haemophilia


Sex-linked genetic disorders are any diseases or abnormal conditions that are caused by a defective gene on the X chromosome, one of the sex chromosomes. These disorders may also involve a deviation in the number of X or Y chromosomes.

Examples of sex-linked disorders caused by a single gene defect on the X chromosome include:

  • Duchenne muscular dystrophy, a progressive degeneration of muscle tissue.
  • Turner Syndrome, a disorder in which all or part of one of the female's X chromosomes is missing, is an example of this.
  • Hemophilia, which is a deficiency in one of several blood-clotting factors and causes uncontrollable bleeding
  • Fragile-X syndrome, a problem witih the FMR1 gene on the X chromosome, which can cause mental retardation

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