Which one of the following hormone never reaches to cytoplasm?

Estrogen

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FSH

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Progesterone

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Testosterone

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Solution

The correct option is C FSH
FSH is a proteinaceous hormone. It does not enter its target cells, thus, it never reaches to cytoplasm. Instead, it binds to the receptor present on the cell membrane and activates a membrane bound enzyme that causes conversion of ATP to cAMP. This then alters the activities of enzyme in the cytoplasm.

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