Which one of the following is a base analogue?

Nitrous acid

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Colchicine

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5 - bromouracil

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Caffeine

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Solution

The correct option is C 5 - bromouracil
5 - bromouracil is a brominated derivative of uracil that acts as an antimetabolite or base analog, substituting for thymine in DNA, can induce DNA mutation in the same way as 2-aminopurine. It is used mainly as an experimental mutagen.

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