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Question
Which one of the following is most carcinogenic, present in tobacco smokeless products?
Which one of the following is most carcinogenic, present in tobacco smokeless products?
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Solution
The correct option is D Benzopyrene
Benzopyrene is a polycyclic aromatic hydrocarbon found in coal tar with the formula C20H12. Its metabolites are mutagenic and highly carcinogenic, and it is listed as a Group I carcinogen by the IARC. Benzopyrene has since been identified as a prime carcinogen in cigarette smoke. When the body attempts to metabolise benzopyrene, the resulting diol epoxide reacts and binds to DNA, resulting in mutations and eventually cancer. So, the correct answer is option B.
Benzopyrene is a polycyclic aromatic hydrocarbon found in coal tar with the formula C20H12. Its metabolites are mutagenic and highly carcinogenic, and it is listed as a Group I carcinogen by the IARC. Benzopyrene has since been identified as a prime carcinogen in cigarette smoke. When the body attempts to metabolise benzopyrene, the resulting diol epoxide reacts and binds to DNA, resulting in mutations and eventually cancer.
So, the correct answer is option B.
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