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Question

Which one of the following is the most likely root cause, why menstruation is not taking place in regularly cycling human female?

A
Maintenance of high concentration of sex-hormones in the blood stream.
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B
Retention of well developed corpus luteum.
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C
Fertilization of the ovum.
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D
All of the above
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Solution

The correct option is D All of the above
A high blood concentration of progesterone and oestrogen will delay or stop menstruation. A high concentration of sex hormone inhibits ovulation and implantation, as well as alter the quality of cervical mucus to prevent / retard entry of sperms. This happens because high concentration of circulating progesterones are an indication of successful conception and pregnancy. Hence, secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from pituitary is inhibited.

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