Question

Which one of the following mutation partially or fully reverses the harmful effects of previous mutation?

• A. Indirect suppression
• B. Intergenic mutation
• C. Intragenic mutation
• D. Suppressor mutation

Answer 1

Answer: (D)

Suppressor mutation

A suppressor mutation can be defined as the mutation (second) which takes place at the site other than that of the previous (first) mutation, which suppresses the phenotypic effect of the first mutation. For example, the mutation in the tDNA is said to suppress the phenotypic effect of the first mutation in a protein-coding gene, and the suppressor tRNA may allow enough of the mRNA to be translated to allow a standard phenotype.

So, the correct option is D.