Question

Which one of the following occurs in chloride shift?

• A. At tissue level ${\text{HCO}}_3^{–}$ ion diffuse out into plasma and ${\text{Cl}}^{–}$ ion enter into $\text{RBC}$
• B. In alveoli ${\text{Cl}}^{–}$ moves out and ${\text{HCO}}_3^{–}$ moves in $\text{RBC}$
• C. ${\text{CO}}_2$ moves into $\text{RBC}$ and ${\text{O}}_2$ moves out in alveoli
• D. Both $\text{(1)}$ and $\text{(2)}$

Answer 1

The correct option is A At tissue level ${\text{HCO}}_3^{–}$ ion diffuse out into plasma and ${\text{Cl}}^{–}$ ion enter into $\text{RBC}$

Chloride shift or Hamburger shift is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate $\left({\text{HCO}}_3^{-}\right)$ and chloride $\left({\text{Cl}}^{-}\right)$ ions across the membrane of red blood cells.


So, the correct answer is option 'a'