A) In prophase, chromosomes are not clearly visible because the sister chromatids are intertwined with each other. The chromosomes overlap one another and appear like a ball of wool, thus, the ends of the chromosomes are not clear.
B) During metaphase, the chromosomes are condensed. Hence, the centromere and the arms of the chromatids are distinct and clearly visible. Due to this, metaphase is best stage to view the shape, size and number of chromosomes.
C) In telophase, the chromosomes undergo elongation and they are at the poles and are diffused in the form of loosely arranged chromatin material. This diffused chromatin material do not show distinct centromeres and chromatids.
D) In interphase, though the duplication of chromatin material takes place, the chromatin material is not condensed to form chromosomes. Hence, chromosomes do not show distinct centromeres and chromatids.
So, the correct answer is 'Metaphase'.