The correct option is C Penetration of leucocytes from blood capillaries into surrounding space.
A long bone consists of a shaft, known as diaphyses, and two expended ends which in turn are called as epiphyses.
Fall in albumin level of blood plasma results in movement of water from blood into the interstitial space causing accumulation of fluid in tissues i.e., edema.
A process wherein leucocytes, drawn by an ancestral cell, leave the venule through invisible holes is known as diapedesis. These migrating leucocytes either lie within the venular wall or pass it and enter the surrounding blood tissues.
In absence of canines, there is wide gap between incisors and premolars. Since, diastema is the gap between two adjacent teeth of same arch that do not touch each other; the gap between premolars and incisors is termed as diastema.
Therefore, the correct answer is option C.