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Question

Which one of the following substances does not pass across membranes by simple diffusion?

A
O2
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B
CO2
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C
H+
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D
H2O
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Solution

The correct option is B H+
Water diffusion is called osmosis. Oxygen is a small molecule and it is nonpolar, so it easily passes through a cell membrane. Carbon dioxide, the byproduct of cell respiration, is small enough to readily diffuse out of a cell. Hydrogen ion cannot pass through a plain phospholipid bilayer, it only passes by binding with another molecule.
So, the correct option is 'H+'.

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