The correct option is B 321 and 192
Let us add the pairs to check the pair that has the sum greater than 500
152 + 241 = 393
321 + 192 = 513
99 + 299 = 398
401 + 51 = 452
Therefore, 321 + 192 gives 513 which is more than 500.
Alternative way to solve:
Take 321 as 300. and 192 as 200.
So the sum is: 300 + 200 = 500. Hence sum of 321 and 192 is closer to 500.
Similarly, round off values in other options and verify them:
For 152 and 241: 150 + 250 = 400
For 99 and 299: 100 + 300 = 400
For 401 and 51; 400 + 50 = 450
So it is clear that all the other options are less than 500.