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Question

Which reaction is unique to gluconeogenesis?


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Solution

Gluconeogenesis:

  1. The process of preparing glucose/sugar from its own byproducts or those of lipids, fats, or proteins is termed Gluconeogenesis.
  2. Gluconeogenesis occurs mostly within liver and kidney cells.
  3. It regulates acid-base homeostasis and amino acid metabolism.

Reaction Unique To Gluconeogenesis:

  1. The process in which pyruvate is carboxylated to yield oxaloacetate is unique to Gluconeogenesis.
  2. Pyruvate carboxylase catalyzes the reaction. It is one of two processes that are essential for the processing of pyruvate to phosphoenolpyruvate (PEP).
  3. PEP is transformed to pyruvate in glycolysis by the action of pyruvate kinase, which is an irreversible event that necessitates an alternative route in gluconeogenesis.

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