Question

Which substance functions during the cell cycle in a regulatory role to prevent cancer?

• A. Cyclin A
• B. MPF
• C. Cycl in D
• D. p53 protein
• E. CDK

Answer 1

The correct option is D p53 protein

A. Cyclin A regulates the progression of cell cycle at S/G2 boundary and G2/M boundary.

B. MPF or M-phase promoting factor is Cyclin B which regulates the progression of cell cycle at G2/M boundary.

C. Cyclin D regulates the progression of cell cycle at G1/S boundary.

D. p53 protein is also known as cellular tumour antigen. Activity of this protein prevent tumour formation.

E. CDK or cyclin dependent kinases are the enzymes that regulate the cell cycle by phosphorylating the amino acids like serine and threonine.

Hence the substance that functions during the cell cycle in a regulatory role to prevent cancer is p53 protein.

So, the correct answer is 'p53 protein'.