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Question

Which vector can clone only a small fragment of DNA?

A
Bacterial artificial chromosome
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B
Yeast artificial chromosome
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C
Plasmid
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D
Cosmid
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Solution

The correct option is C Plasmid
Most plasmids may be used to clone DNA insert of only up to 15 kb (kilobase) in size.
Cosmid may be used to clone DNA inserts up to 45 kb in size.
Bacterial Artificial Chromosome (BAC) may be used to clone DNA inserts up to 150-350 kb.
Yeast Artificial Chromosome (YAC) may be used to clone DNA inserts up to 100-1000 kb.

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