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Question

Which was the first product contributed to human kind by science of biotechnology in early 1972?

A
Somatotropin
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B
Insulin
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C
Cytokines
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D
Erythropoietin
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Solution

The correct option is A Somatotropin
Identification of the biochemical structure of GH in 1972 became the catalyst for the development of recombinant DNA-derived human GH, the gene for which was cloned for the first time in 1979. An improved process to develop recombinant human GH (rhGH) is called protein secretion technology. Wherein, the vector plasmid is isolated from a strain of E. coli and the DNA strand to be cloned is derived from the appropriate source. Both the plasmid and the required DNA strand are cleaved by restriction enzymes, joined together and then reformed into a circular structure. The recombinant plasmid is inserted into E. coli, which is then transformed to synthesize the desired protein This is currently the most common method used to synthesize rhGH, known generically as somatotropin.

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