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Question

Who amongst the following scientists discovered cytochemical technique to detect DNA?

A
Waston and Crick
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B
Wilkins
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C
Feulgen and Rossenbeck
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D
Gierer and Schramm
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Solution

The correct option is C Feulgen and Rossenbeck
Basic dyes stain chromosomes and other nuclear structures. Examples of such dyes are basic fuchsin, crystal violet, methyl green, safranin, Feulgen or Schiff's Reagent. Feugel was developed by Feulgen and Rossenbeck in 1924. It employs basic fuchsin after acid hydrolysis. The reaction is specific for DNA. Acid hydrolase separates purines and exposes aldehyde groups of deoxyribose sugar which react with Schiff's reagent to produce the stain.
So, the correct answer is option C.

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