Question

Who isolated the first restriction endonuclease?

Answer 1

Restriction endonuclease:

1. Restriction endonuclease also known as restrictive enzymes are mainly present in prokaryotes.
2. The main function of this enzyme is to protect the organism from foreign DNA or RNA mainly bacteriophage.
3. They cut through the foreign genetic material from the restriction sites.
4. Hamilton O. Smith was the first person to isolate the restrictive enzyme from the bacterium Haemophilus influenzae.
5. The first enzyme to be isolated was HindII and it could cut from the specific six-base pair.