The correct option is A Heparin
Heparin is an anticoagulant, which prevents the conversion of prothrombin into thrombin. The molecular basis for the anticoagulant action of heparin lies in its ability to bind to and enhance the inhibitory activity of the plasma protein anti-thrombin against several serine proteases of the coagulation system, most importantly factors IIa (thrombin), Xa and IXa.
So, the correct answer is -heparin.