Question

Who proposed the first lamellar model?

Answer 1

The first lamellar model was proposed by James Danielli and Hugh Davson in 1935 on the basis of their physiological studies. According to Danielli and Davson, a biomembrane contains four molecular layers, two of phospholipids and two of proteins. Phospholipids form a double layer. The phospholipid bilayer is covered on either side by a layer of hydrated globular or $\alpha$-protein molecules. The hydrophilic polar heads of the phospholipid molecules are directed towards the proteins. The two are held together by electrostatic forces. The hydrophobic nonpolar tails of the two lipid layers are directed towards the centre where they are held together by hydrophobic bonds and van der Waals forces.