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Question
Who proposed the 'signal hypothesis' meant for the biosynthesis of secretory type of proteins?
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Solution
The correct option is C Blobel and Sabatini
The "signal hypothesis" describes the pathway of by which secretory and membrane proteins are targeted to the endoplasmic reticulum. This hypothesis proposes that when proteins are destined for secretion, it involves the movement of the protein across a biological membrane. These proteins are originally manufactured with an initial sequence of amino acids that may or may not present in the mature protein. The hypothesis was proposed in 1971 by Günter Blobel and David Sabatini.So, the correct answer is option C.
The "signal hypothesis" describes the pathway of by which secretory and membrane proteins are targeted to the endoplasmic reticulum. This hypothesis proposes that when proteins are destined for secretion, it involves the movement of the protein across a biological membrane. These proteins are originally manufactured with an initial sequence of amino acids that may or may not present in the mature protein. The hypothesis was proposed in 1971 by Günter Blobel and David Sabatini.
So, the correct answer is option C.
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