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Question

Why are gram-negative bacteria usually pathogens?


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Solution

Gram-negative bacteria:

  1. In gram-negative bacteria, the peptidoglycan layer is much thinner than that of gram-positive bacilli.
  2. Gram-negative bacteria are therefore harder to kill because of their harder cell wall.
  3. When their cell wall gets disturbed, the gram-negative bacteria starts releasing endotoxins which could cause problem in already persistent disease making it worsen the condition.

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