● The meristematic cells divide frequently and they give rise to new cells.
●For this they require a dense cytoplasm and thin cell wall.
●Vacuoles if present will cause hinderance in cell division as it is full of cell sap to provide turgidity as well as rigidity to the cell.
●Another reason is that the main function of vacoules is to store nutrients , excess salts etc… and meristamatic cells do not need to store these nutrients because of their compact shape.