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Question

Why do the thigh muscles get tired soon, but not the muscles of the heart?

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Solution

Thigh muscles are skeletal muscles whereas muscles of the heart are cardiac muscles. The cells of cardiac muscles have a greater number of mitochondria than the cells present in skeletal muscle. So, the cells of cardiac muscles get plenty of energy, produced by mitochondria.
Hence, thigh muscles get tired soon but not the muscles of the heart.

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