Question

Why does centrosome duplication occur only once per cell cycle?

Answer 1

Centrosome duplication

1. The centrosome is an organelle that fills in as the fundamental microtubule-organizing center (MTOC) of the cell, as well as a controller of cell-cycle movement.
2. The centrosome gives design, structure, and functional capabilities to the cell.
3. Most microtubule-related functions, such as cell motility, cell division, and cell signaling, depend heavily on centrioles.
4. The number of centrioles needs to be carefully regulated in order to coordinate these various cellular functions.
5. Furthermore, because these processes are co-regulated, the duplication and segregation of centrosomes must be coordinated with the cycle of chromosome duplication and segregation.
6. Centrosome duplication is closely regulated, much like DNA replication, to guarantee that centriole duplication happens only once (cell cycle control) and that only one new centriole is produced for every current centriole (copy number control).