The correct option is D Haemoglobin combines with CO instead of O2 and the product cannot dissociate.
Carbon monoxide is a harmful gas that combines with haemoglobin to form a stable compound. It displaces the oxygen that is normally carried by the haemoglobin and reduces the oxygen-carrying ability of the blood. The affinity between hemoglobin and carbon monoxide is approximately 200 times greater than the affinity between hemoglobin and oxygen, so hemoglobin binds to carbon monoxide in preference to oxygen.