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Question

Why is Hemophilia more common in males?


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Solution

Hemophilia:

  1. It is a genetically inherited disease where the body is unable to stop the flow of blood.
  2. It is an X-linked disease, where an infected individual will continue to bleed even from a minor cut since the patient does not possess the natural phenomenon of blood clotting.
  3. It is mainly due to the absence of antihemophilic globulin or factor VIII (hemophilia – A) and plasma thromboplastin factor IX.
  4. As hemophilia is an X-linked disease, it is more common in males as they have only one X-chromosome, and a defect in one copy of the gene is sufficient to cause the disease.

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