Question

Why is negative-strand DNA synthesized?

Answer 1

Negative-strand DNA:

1. All known animals and many viruses contain genetic information in the form of a polymer called DNA, which is made up of two polynucleotide chains that coil around one another to create a double helix.
2. Nucleic acids are one of the four main categories of macromolecules that are necessary for all known forms of life, along with proteins, lipids, and complex carbohydrates (polysaccharides).
3. The two DNA strands are made up of simpler monomeric units termed nucleotides, they are referred to as polynucleotides.
4. Each nucleotide is made up of a phosphate group, a deoxyribose sugar, and one of the four nitrogen-containing nucleobases (cytosine [C], guanine [G], adenine [A], or thymine [T].
5. To create double-stranded DNA, the nitrogenous bases of the two distinct polynucleotide strands are joined by hydrogen bonds by the base pairing principles (A with T and C with G).
6. Pyrimidines and purines make up the two families of complementary nitrogenous bases.