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Question

Why is RNA primase important for DNA replication?

A
DNA polymerase cannot start replication from a free 5' end
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B
RNA primer added to DNA strand gives stability during replication
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C
A primer is always made of RNA
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D
None of the above
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Solution

The correct option is A DNA polymerase cannot start replication from a free 5' end
DNA polymerase does not have the ability to start the replication from a free 5' end of the DNA; it can only add nucleotides to the free 3' end of an already existing primer. Therefore the RNA primase first creates a short primer of 10-15 nucleotides and then, the DNA polymerase takes over.

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