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Question

Why is the size of chromosomes measured at mitotic metaphase?


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Solution

Metaphase:

  1. The chromosomes are at their second-most compacted and coiled state during the mitotic stage of the eukaryotic cell cycle, known as metaphase.
  2. These chromosomes, which contain genetic material, align in the cell's equator before being divided into the two daughter cells.
  3. Mitotic anaphase differs from metaphase in that it has half as many chromatids and the same number of chromosomes.
  4. During anaphase of mitosis, the chromosomes split at the kinetochore or centromere, resulting in the production of two sister chromatids known as chromosomes.
  5. Further contractions cause the chromosomes to become most distinct during metaphase.
  6. As a result, the mitotic metaphase is when chromosome size is calculated.

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