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Question

With the help of an algebraic equation, how did Hardy-Weinberg explain that in a given population the frequency of occurrence of alleles of a gene is supposed to remain the same through generations? [2]

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Solution

According to Hardy–Weinberg principle the allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences [1]

In a population of diploid organisms. [0.5]
If frequency of allele A = p
And frequency of allele a = q, then the expected genotype frequency under random mating are -
AA=P2 (for AA homozygotes)
aa=q2 (for aa homozygotes)
Aa =2pq (for Aa heterozygotes)

In the absence of selection, mutation, genetic drift or other forces, p and q are constatnt through generations.

Therefore, p2+2pq+q2=1 [0.5]

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