Endoplasmic Reticulum is three-dimensional networks of intracellular membranes. It is present in all eukaryotic cells. In young meristematic cells, ER is very much developed. In spermatocytes, ER is represented by a few vacuoles. Cells actively synthesising proteins like liver, fibroblast and pancreatic cells have abundant ER.
1. ER is formed of three types of elements.
- They are sacs like unbranched structures.
- It lies in stacks or piles parallel to each other. These cisternae in the stack are interconnected with each other.
- Cisternae contain transmembrane Glycoprotein Ribophorin 2, they bind with larger subunits of the ribosome.
- Cytosolic spaces are present between Cisternae.
- These are irregular branched tubular structures.
- They form a network along with other elements.
- These are oval, rounded vacuole-like elements.
- It is often isolated in the cytoplasmic matrix.
2. There is two type of ER :
- Smooth ER or Smooth Endoplasmic Reticulum: Ribosome is not present in SER. It is generally peripheral in position & connected with the plasma membrane.
- Rough ER (RER) or Rough Endoplasmic Reticulum: RER is present in the Ergastoplasm. RER is generally internal in position & are connected with the nuclear envelope.
3. Functions of ER :
• It provides mechanical support and acts as endoskeleton or cytoskeleton of the cell.
• Sarcoplasmic Reticulum relates Ca++ which helps in muscle contraction.
• The Ca++ plays an important role in the fusion of vesicles in cell plate formation and also helps in the movement of chromosomes.
• RER in association with Golgi complex give rise to Lysosomes.
• ER keeps various cell organelles in their position.