Question

Write briefly about Bohr effect and Haldane effect and their significance.

Answer 1

The Bohr effect is a physiological phenomenon first described in 1904 by the Danish physiologist Christian Bohr, states that hemoglobin's oxygen binding affinity is inversely related both to acidity and to the concentration of carbon dioxide. Bohr effect works when blood nears the lungs and the carbon dioxide concentration decreases, causing an increase in pH. This increase in pH increases hemoglobin's affinity for oxygen through the Bohr effect, causing hemoglobin to pick up oxygen entering the blood from the lungs so it can transport it to your tissues.

The Haldane effect is a property of hemoglobin first described by John Scott Haldane. Oxygenation of blood in the lungs displaces carbon dioxide from hemoglobin which increases the removal of carbon dioxide. This property is the Haldane effect. Conversely, oxygenated blood has a reduced affinity for carbon dioxide.