Write short note on organ- specific and tissue-specific manifestations of disease.
Organ-specific manifestation- these are the diseases caused in the same organ or organ system as the point of entry of the microbe. e.g. Tuberculosis which enters through the nose and affects the lungs. (Both are organs of the respiratory system)
Tissue-specific manifestation- these are the diseases caused in a different organ as the point of entry. E.g. Japanese Encephalitis enters through the blood but affects the brain.