Question

Write the main steps in the coagulation of blood in their correct sequence?

Answer 1

Blood clotting or coagulation occurs in a series of the following steps:

• The injured tissue cells and the platelets disintegrate at the site of the wound to release thromboplastin.
• The thromboplastin with the help of calcium ions converts inactive prothrombin into active thrombin.
• Thrombin in the presence of calcium ions converts soluble fibrinogen into insoluble fibrin which forms a mesh or network at the site of the wound.
• The blood cells trapped in this network shrink and squeeze out the plasma to leave behind a solid mass known as the clot.