The correct option is A Y chromosome is the sex determining factor.
XX Drosophila is female but XXY human is an abnormal male. This clearly indicates that Y chromosome is sex determining factor. Human females carry XX sex chromosomes. The Y-chromosome carries SRY gene which encodes TDF (Testis Determining Factor). The TDF serves as transcription factor that binds to specific DNA sequence to start the process to develop the embryo into male child. Hence, presence of one Y chromosome in a female causes abnormality in them. Option B is correct answer.