How does nucleoside differ from nucleotide?


Both nucleotide and nucleoside have pentose sugar and nitrogenous base. Nucleotide differs from nucleoside with the presence of phosphoric acid as nucleoside do not have phosphoric acid.

  • They are building blocks of nucleic acid, as nucleotides consist of the same components such as a nitrogenous base, sugar and a phosphate group.
  • The key difference is that nucleosides contain only sugar and a base, while nucleotides contain sugar, base, and a phosphate group.
  • A nucleotide comes before RNA and DNA, and a nucleoside comes before the nucleotide itself.

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