A checkpoint is a stage in the eukaryotic cell cycle at which the cell examines internal and external cues and “decides” whether to move forward with the division.
Three main checkpoints in the cell cycle:
- Phase G1: In this phase DNA integrity and cell size takes place
- ii) Phase G2: This is the phase where DNA damage and chromosome duplication takes place
- iii) Phase M: Attachment of kinetochore and a spindle fibre takes place