Question

Which of the following is correct for reaction of chiral substrate?

• A. A reaction in which different stereoisomers produce different products or act at different rates is called a stereospecific reaction.
• B. A reaction in which a given substrate produces diastereoisomeric products in different amounts and where one diastereomer predominates very much over the other is called stereoselective reaction.
• C. If the replacement of one group at an a chiral centre by a new substituent generates a chiral centre, the original molecule is said to be enantiotopic.
• D. The E and Z system of naming geometrical isomers is based on the CIP rule.

Answer 1

Answer: (A), (B), (C), (D)

The E and Z system of naming geometrical isomers is based on the CIP rule.

Explanation for correct answer:-

Option (A)

• We know that a reaction in which different stereoisomers produce different products or act at different rates is called a stereospecific reaction.
• In other we can say that two stereoisomers react to produce two different stereoisomers and they have different rates as well.
• Hence this statement is correct.

Option (B)

• A reaction in which a given substrate produces diastereoisomeric products in different amounts and where one diastereomer predominates very much over the other is called a stereoselective reaction.
• For example when a compound reacts it produces cis and trans products, out of this if anyone is major and the other is minor, then it becomes a stereoselective reaction.
• Hence this statement is correct.

Option (C)

• If the replacement of one group at a chiral center by a new substituent generates a chiral center, the original molecule is said to be enantiotopic.
• In other words if a substituent of a chiral carbon gets replaced by another substituent and forms a new compound with the same chiral carbon, then the original molecule is said to be an enantiotopic compound.
• Hence this statement is also correct.

Option (D)

• The E and Z system of naming geometrical isomers is basically based on the CIP rule(Cahn-Ingold-Prelog).
• According to this sequence rule, an atom that has a higher atomic number is given higher priority.
• Hence this statement is also correct.

Therefore, option (A), (B), (C), (D) are the correct answer.