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Question

The first phase of translation is:

A
Aminoacylation of tRNA
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B
Recognition of an anticodon
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C
Binding of mRNA to ribosome
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D
Recognition of DNA molecule
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Solution

The correct option is A Aminoacylation of tRNA
Translation refers to the process in which the amino acids get polymerised to form a polypeptide chain, the sequence of which is determined by the order of bases present in mRNA.
Joining of amino acids requires the formation of peptide bonds which is an energy-requiring process.
Hence, the first phase in translation is the activation of amino acids in the presence of ATP. The activated amino acids are then linked to their cognate tRNAs, a process commonly called as charging of tRNA or aminoacylation of tRNAs.

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