Question

What are the three alleles responsible for the ABO blood system?

Answer 1

ABO Blood:

1. Blood is the main component of the circulation system and the connective tissue that is fluid in nature.
2. There are four types in the ABO blood group. They are A, B, AB, and O that mainly depend on the antibody and antigens of blood in cells and plasma.

In humans, ABO is regulated by three alleles known as I^A, I^B, and I^O.

1. Here I refers to haemagglutinin, i.e., a group of glycoproteins responsible for blood clotting.
2. I^A and I^B are codominant, producing antigens of Type A and Type B respectively.
3. They are shifted to the surface of RBCs whereas the I^O is recessive, producing no antigens.