Question

What can modify DNA molecules?

Answer 1

DNA modification:

1. Any change in DNA sequence or its structure is referred as DNA modification.
2. Several enzymes which are capable of doing this modifications.
3. DNA ligase: Ligase is an enzyme which joins together the Okazaki fragments of the discontinuous DNA strands.
4. Alkaline phosphatase: It is responsible for removing phosphate group from the 5' terminal of the DNA strand.
5. Polynucleotide kinase: Responsible for adding phosphate group at the 5' terminal of the DNA strand.
6. Terminal deoxynucleotidyl transferase: At 3' end of the DNA molecule, this enzyme causes addition of deoxyribonucleotides.