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Question

What is correct to say about the hormone action in humans?


A

Secretion of thymosins is stimulated with aging.

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B

Glucagon is secreted by β-cells of islets of Langerhans and stimulates glycogenolysis.

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C

FSH stimulates the secretion of estrogen and progesterone.

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D

In females, FSH first binds with specific receptors on the ovarian cell membrane.

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Solution

The correct option is D

In females, FSH first binds with specific receptors on the ovarian cell membrane.


The correct answer is option D.

Explanation of the correct answer:

  1. Gonadotropin-releasing hormone (GnRH) stimulates the pituitary gland to produce follicle-stimulating hormone (FSH).
  2. Follicle-stimulating hormone is a glycoprotein peptide hormone secreted by the anterior pituitary gland, which is responsible for stimulating the growth of ovarian follicles.
  3. Being a peptide hormone, FSH regulates cellular metabolism by binding with the membrane-bound receptors present on the cells of the ovary.
  4. After interacting with the membrane-bound receptors, it generates a secondary messenger such as cyclic AMP or Ca++. FSH stimulates the secretion of estrogen from the ovary.

Explanation of the incorrect options:
Option A: Thymosins are peptide hormones secreted by the thymus gland. These hormones stimulate the development of immature T cells into mature T cells. Since the thymus gland keeps on getting reduced in size with age, the secretion of thymosins also gets reduced with increasing age.
Option B: Glucagon is a peptide hormone secreted by the alpha cells of the islets of Langerhans, which helps to maintain glucose homeostasis in the blood along with insulin. It acts antagonistic to insulin, i.e., promotes the breakdown of glycogen to glucose (glycogenolysis).
Option C: Follicle-stimulating hormone and luteinizing hormone are responsible for the rise in estrogen and progesterone levels.

Final answer: Action of hormones in humans In females, FSH first binds with specific receptors on the ovarian cell membrane.


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