Question

What is the difference between frameshift mutation and point mutation?

Answer 1

Point change:

1. Point mutation is a genetic mutation where a nucleotide base is altered, inserted, or deleted from the DNA or RNA sequence of an organism's genome.

Frameshift change:

1. A frameshift mutation is a genetic change brought on by an insertion or deletion that changes how the DNA sequence is read.
2. A chain of numerous smaller molecules known as nucleotides makes up a DNA sequence.

Difference between frameshift mutation and point mutation:

Point Mutation	Frameshift Mutation
1. A gene mutation that involves substituting, deleting, or inserting a base pair is called a point mutation.	1. Some chemical mutagenesis enters between the two bases of the DNA chain and results in the addition or deletion of some bases. This coding results in a side shift of the frame, from where all the codons change. Such a mutation is called a frameshift mutation.
2. It involves transitions and changes.	2. It involves insertion and deletion.
3. This results in a change in the structure of the gene.	3. It results in a change in the number of nucleotides.
4. It causes diseases like sickle cell anemia.	4. It causes diseases like cystic fibrosis and Crohn's disease.