Question

What was the basis for the discovery of the condensin complex?

Answer 1

Condensin complex:

1. Condensin complex is a complex made up of protein that is used to condense the chromosome during mitosis.
2. This complex makes sure that the chromatin fibers condense into a chromosome.
3. Condensin plays an important role in the cell cycle as it helps in condensation.
4. It also plays an important role in changing the organization of the genome.
5. This was the main basis for the discovery of the condensin complex.
6. Suppression of the condensin I or II in the cells of humans (via RNA interference) could lead to condensation defects.
7. Mutations in any one of the five condensin subunits of fission yeast or budding yeast lead to defects in the relatively limited chromosome condensation that occurs in these species